- Title
- Bladder carcinoma in situ (CIS) in Australia: a rising incidence for an under-reported malignancy
- Creator
- Ranasinghe, Weranja K.B.; Attia, John; Oldmeadow, Christopher; Lawrentschuk, Nathan; Robertson, Jane; Ranasinghe, Tamra; Bolton, Damien; Persad, Raj
- Relation
- BJU International: Special Issue: Urological Society of Australia and New Zealand Supplement Vol. 112, Issue S2, p. 46-52
- Publisher Link
- http://dx.doi.org/10.1111/bju.12052
- Publisher
- Wiley-Blackwell Publishing
- Resource Type
- journal article
- Date
- 2013
- Description
- Objectives: To investigate the incidence of carcinoma in situ (CIS) in Australia and examine implications for its diagnosis and management, as CIS of the urinary bladder is a non-reportable disease in Australia. Methods: * Analysis of annual hospitalisation data using Australian Institute of Health and Welfare (AIHW) datasets showed an increase in CIS from 2001 onwards. * To determine whether the increase seen with AIHW data represented a true increase in the rates offices, patient level data was examined using the Centre for Health record linkage (CHeReL) datasets. Results * CHeReL linked data of 13790 males and 5902 females, calculated the average incidence of CIS to be 20.9 per 100,000 and 6.5 per 100,000 respectively in those aged > 50 years, showing a rapid increase in the rates of CIS from 2001. * There was an 11% (P = 0.04) and 14% (P = 0.02) annual increase in incidence of CIS in men and women and these rates increased with age. Conclusions * National data (AIHW) substantially underestimate the incidence of CIS in the Australian population. * Patient level data suggest CIS rates are rapidly increasing in Australia despite high treatment rates. * Closer surveillance and awareness of these high rates warrants further study and we recommend that CIS be considered a reportable disease.
- Subject
- bladder carcinoma; carcinoma in situ; Australia
- Identifier
- http://hdl.handle.net/1959.13/1067614
- Identifier
- uon:18447
- Identifier
- ISSN:1464-410X
- Language
- eng
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